Antibiotic Treatment of Suspected Neonatal Meningitis

Antibiotic treatment of suspected neonatal meningitis.

Intrathecal antibiotic therapy for neonatal meningitis.

Twenty infants with neonatal meningitis were treated with systemic and lumbar intrathecal antibiotics upon initial diagnosis. Failure to sterilize the CSF in 2-3 days was associated with evidence of ventriculitis in these infants who were then treated with intraventricular antibiotics. 4 infants died, but only 2 of them may be regarded as treatment failure. It is suggested that many deaths from...

Frequency of Neonatal and children bacterial meningitis and determining their antibiotic sensitivity patterns in Hospitals of Iran

Meningitis is one of the most important causes of infant mortality and its early and proper diagnosis is of great importance, but there are currently no laboratory facilities optimized and fast in detection of meningitis pathogens. The current standard of bacterial meningitis diagnosis is microscopic examination and cerebrospinal fluid (CSF) culture. This research aimed at isolating the most co...

Neonatal meningitis

Twelve years ago an annotation was published in Archives of Disease in Childhood regarding the antibiotic treatment of suspected neonatal meningitis. The authors recommended the use of cephalosporins rather than chloramphenicol and advocated intraventricular aminoglycoside treatment in selected cases. They noted the absence of clinical trials with third generation cephalosporins that showed an ...

Neonatal meningitis.

Some of the main features of neonatal meningitis, studied in a defined population of infants, are reviewed. The incidence rate was twenty-six cases per 100 000 live-births. The case fatality rate was 43%. Gram-negative intestinal bacilli were the commonest infecting organisms. Streptococci accounted for an important minority of cases. It is stressed that neonatal meningitis usually presents as ...